Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformation.

We have constructed a transformation-defective polyoma virus mutant (Py 1387-T) that directs the synthesis of a normal small tumor antigen, a functional large tumor antigen, and a truncated (51,000-dalton) middle-sized tumor (mT) antigen that lacks 37 amino acids at its COOH terminus. The shortened...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Carmichael, G G, Schaffhausen, B S, Dorsky, D I, Oliver, D B, Benjamin, T L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6179082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3579
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