Use of un-derivatized thyroid hormones for photoaffinity labeling of binding proteins.
Irradiation of the thyroid hormones thyroxine and 3,5,3'-triiodothyronine in the near UV (greater than 300 nm) causes homolytic fission of C--I bonds in both rings. In the presence of hormone-binding proteins, the phenyl radical thus formed, and possibly also the iodine radical, can establish a cova...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1982
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3508 |
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