The Association between a Polygenic Alzheimer Score and Cortical Thickness in Clinically Normal Subjects

Late-onset Alzheimer's disease (AD) is 50–70% heritable with complex genetic underpinnings. In addition to Apoliprotein E (APOE) ε4, the major genetic risk factor, recent genome-wide association studies (GWAS) have identified a growing list of sequence variations associated with the disease. Bu...

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Autors principals: Sabuncu, Mert R., Buckner, Randy L., Smoller, Jordan W., Lee, Phil Hyoun, Fischl, Bruce, Sperling, Reisa A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464416/
https://ncbi.nlm.nih.gov/pubmed/22169231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhr348
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