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Overcoming Sequence Misalignments with Weighted Structural Superposition

An appropriate structural superposition identifies similarities and differences between homologous proteins that are not evident from sequence alignments alone. We have coupled our Gaussian-weighted RMSD (wRMSD) tool with a sequence aligner and seed extension (SE) algorithm to create a robust techni...

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Detalhes bibliográficos
Main Authors: Khazanov, Nickolay A., Damm-Ganamet, Kelly L., Quang, Daniel X., Carlson, Heather A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464347/
https://ncbi.nlm.nih.gov/pubmed/22733542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24134
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