Aurora A kinase expression is increased in leukemia stem cells, and a selective Aurora A kinase inhibitor enhances Ara-C-induced apoptosis in acute myeloid leukemia stem cells

BACKGROUND: The overexpression of Aurora A kinase (AurA) has been reported in various malignancies, including acute myeloid leukemia (AML). However, the expression of AurA and the effects of AurA inhibition in cancer stem cells are not yet fully understood. We investigated the expression and inhibit...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kim, Soo-Jeong, Jang, Ji Eun, Cheong, June-Won, Eom, Ju-In, Jeung, Hoi-Kyung, Kim, Yundeok, Hwang, Doh Yu, Min, Yoo Hong
التنسيق: Artigo
اللغة:Inglês
منشور في: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2012
الموضوعات:
Original Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464334/
https://ncbi.nlm.nih.gov/pubmed/23071472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/kjh.2012.47.3.178
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