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Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure.
When rat pancreatic polynucleosomes were poly(ADP-ribosyl)ated with purified calf thymus poly(ADP-ribose) polymerase and examined by electron microscopy, a relaxation of their native zigzag structure was observed. At high ionic strengths control nucleosomes condensed into 250-A-thick fibers, but pol...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6808510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3423 |
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