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The NMR Structure of Human Obestatin in Membrane-Like Environments: Insights into the Structure-Bioactivity Relationship of Obestatin

The quest for therapeutic applications of obestatin involves, as a first step, the determination of its 3D solution structure and the relationship between this structure and the biological activity of obestatin. On this basis, we have employed a combination of circular dichroism (CD), nuclear magnet...

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Detalhes bibliográficos
Main Authors: Alén, Begoña O., Nieto, Lidia, Gurriarán-Rodríguez, Uxía, Mosteiro, Carlos S., Álvarez-Pérez, Juan C., Otero-Alén, María, Camiña, Jesús P., Gallego, Rosalía, García-Caballero, Tomás, Martín-Pastor, Manuel, Casanueva, Felipe F., Jiménez-Barbero, Jesús, Pazos, Yolanda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464274/
https://ncbi.nlm.nih.gov/pubmed/23056203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045434
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