Deregulated Sex Chromosome Gene Expression with Male Germ Cell-Specific Loss of Dicer1

MicroRNAs (miRNAs) are a class of endogenous, non-coding RNAs that mediate post-transcriptional gene silencing by inhibiting mRNA translation and promoting mRNA decay. DICER1, an RNase III endonuclease encoded by Dicer1, is required for processing short 21–22 nucleotide miRNAs from longer double-str...

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Detalhes bibliográficos
Main Authors: Greenlee, Anne R., Shiao, Meng-Shin, Snyder, Elizabeth, Buaas, F. William, Gu, Tongjun, Stearns, Timothy M., Sharma, Manju, Murchison, Elizabeth P., Puente, Gabriella C., Braun, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464243/
https://ncbi.nlm.nih.gov/pubmed/23056286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046359
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