Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation

BACKGROUND: Neuroinflammation, caused by six days of intracerebroventricular infusion of bacterial lipopolysaccharide (LPS), stimulates rat brain arachidonic acid (AA) metabolism. The molecular changes associated with increased AA metabolism are not clear. We examined effects of a six-day infusion o...

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Détails bibliographiques
Auteurs principaux: Kellom, Matthew, Basselin, Mireille, Keleshian, Vasken L, Chen, Mei, Rapoport, Stanley I, Rao, Jagadeesh S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464147/
https://ncbi.nlm.nih.gov/pubmed/22621398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-50
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