Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation

BACKGROUND: Neuroinflammation, caused by six days of intracerebroventricular infusion of bacterial lipopolysaccharide (LPS), stimulates rat brain arachidonic acid (AA) metabolism. The molecular changes associated with increased AA metabolism are not clear. We examined effects of a six-day infusion o...

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Main Authors: Kellom, Matthew, Basselin, Mireille, Keleshian, Vasken L, Chen, Mei, Rapoport, Stanley I, Rao, Jagadeesh S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464147/
https://ncbi.nlm.nih.gov/pubmed/22621398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-50
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