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PUF-8, a Pumilio Homolog, Inhibits the Proliferative Fate in the Caenorhabditis elegans Germline

Stem cell populations are maintained by keeping a balance between self-renewal (proliferation) and differentiation of dividing stem cells. Within the Caenorhabditis elegans germline, the key regulator maintaining this balance is the canonical Notch signaling pathway, with GLP-1/Notch activity promot...

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Autors principals: Racher, Hilary, Hansen, Dave
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464112/
https://ncbi.nlm.nih.gov/pubmed/23050230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.003350
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