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Cyclin A(1) Is Essential for Setting the Pluripotent State and Reducing Tumorigenicity of Induced Pluripotent Stem Cells

The proper differentiation and threat of cancer rising from the application of induced pluripotent stem (iPS) cells are major bottlenecks in the field and are thought to be inherently linked to the pluripotent nature of iPS cells. To address this question, we have compared iPS cells to embryonic ste...

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Библиографические подробности
Главные авторы: McLenachan, Samuel, Menchón, Cristina, Raya, Angel, Consiglio, Antonella, Edel, Michael J.
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464069/
https://ncbi.nlm.nih.gov/pubmed/22500553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0190
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