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Cyclin A(1) Is Essential for Setting the Pluripotent State and Reducing Tumorigenicity of Induced Pluripotent Stem Cells

The proper differentiation and threat of cancer rising from the application of induced pluripotent stem (iPS) cells are major bottlenecks in the field and are thought to be inherently linked to the pluripotent nature of iPS cells. To address this question, we have compared iPS cells to embryonic ste...

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Detalhes bibliográficos
Main Authors: McLenachan, Samuel, Menchón, Cristina, Raya, Angel, Consiglio, Antonella, Edel, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464069/
https://ncbi.nlm.nih.gov/pubmed/22500553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0190
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