Crystal Structure of the Marburg Virus GP2 Core Domain in its Post-Fusion Conformation

Marburg virus (MARV) and Ebola virus (EBOV) are members of the family Filoviridae (‘filoviruses’) that cause severe hemorrhagic fever with human case fatality rates of up to 90%. Filovirus infection requires fusion of the host cell and virus membranes, a process that is mediated by the envelope glyc...

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Détails bibliographiques
Auteurs principaux: Koellhoffer, Jayne F., Malashkevich, Vladimir N., Harrison, Joseph S., Toro, Rafael, Bhosle, Rahul C., Chandran, Kartik, Almo, Steven C., Lai, Jonathan R.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464016/
https://ncbi.nlm.nih.gov/pubmed/22935026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300976m
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