Betulinic Acid Inhibits Growth of Cultured Vascular Smooth Muscle Cells In Vitro by Inducing G(1) Arrest and Apoptosis

Betulinic acid is a widely available plant-derived triterpene which is reported to possess selective cytotoxic activity against cancer cells of neuroectodermal origin and leukemia. However, the potential of betulinic acid as an antiproliferative and cytotoxic agent on vascular smooth muscle (VSMC) i...

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Autores principales: Vadivelu, Raja Kumar, Yeap, Swee Keong, Ali, Abdul Manaf, Hamid, Muhajir, Alitheen, Noorjahan Banu
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463985/
https://ncbi.nlm.nih.gov/pubmed/23056140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/251362
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