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Betulinic Acid Inhibits Growth of Cultured Vascular Smooth Muscle Cells In Vitro by Inducing G(1) Arrest and Apoptosis

Betulinic acid is a widely available plant-derived triterpene which is reported to possess selective cytotoxic activity against cancer cells of neuroectodermal origin and leukemia. However, the potential of betulinic acid as an antiproliferative and cytotoxic agent on vascular smooth muscle (VSMC) i...

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Main Authors: Vadivelu, Raja Kumar, Yeap, Swee Keong, Ali, Abdul Manaf, Hamid, Muhajir, Alitheen, Noorjahan Banu
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463985/
https://ncbi.nlm.nih.gov/pubmed/23056140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/251362
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