Quantitative analyses of DAPK1 methylation in AML and MDS

Aberrant DNA methylation and concomitant transcriptional silencing of death-associated protein kinase 1 (DAPK1) have been demonstrated to be key pathogenic events in chronic lymphocytic leukemia (CLL). In acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), however, the presence of eleva...

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Main Authors: Claus, Rainer, Hackanson, Björn, Poetsch, Anna R., Zucknick, Manuela, Sonnet, Miriam, Blagitko-Dorfs, Nadja, Hiller, Jan, Wilop, Stefan, Brümmendorf, Tim H., Galm, Oliver, Platzbecker, Uwe, Byrd, John C., Döhner, Konstanze, Döhner, Hartmut, Lübbert, Michael, Plass, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463871/
https://ncbi.nlm.nih.gov/pubmed/21918973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26429
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