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Inhibition of Notch Signaling by a γ-Secretase Inhibitor Attenuates Hepatic Fibrosis in Rats

Notch signaling is essential to the regulation of cell differentiation, and aberrant activation of this pathway is implicated in human fibrotic diseases, such as pulmonary, renal, and peritoneal fibrosis. However, the role of Notch signaling in hepatic fibrosis has not been fully investigated. In th...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Yixiong, Zheng, Shaoping, Qi, Dan, Zheng, Shaojiang, Guo, Junli, Zhang, Shuling, Weng, Zhihong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463607/
https://ncbi.nlm.nih.gov/pubmed/23056328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046512
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