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Roles of Spatial Parameters on the Oscillation of Nuclear NF-κB: Computer Simulations of a 3D Spherical Cell

Transcription factor NF-κB resides in the cytoplasm and translocates to the nucleus by application of extracellular stimuli. It is known that the nuclear NF-κB oscillates and different oscillation patterns lead to different gene expression. Nearly forty reports on modeling and simulation of nuclear...

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Detalhes bibliográficos
Main Authors: Ohshima, Daisuke, Inoue, Jun-ichiro, Ichikawa, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463570/
https://ncbi.nlm.nih.gov/pubmed/23056526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046911
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