α-bisabolol Is an Effective Proapoptotic Agent against BCR-ABL(+) Cells in Synergism with Imatinib and Nilotinib

We showed that α-bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias (ALL). Here we studied the activity of α-bisabolol against BCR-ABL(+) cells using 3 cell lines (K562, LAMA-84, CML-T1) and 10 primary BCR-ABL(+) ALL samples. We found that: (...

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Main Authors: Bonifacio, Massimiliano, Rigo, Antonella, Guardalben, Emanuele, Bergamini, Christian, Cavalieri, Elisabetta, Fato, Romana, Pizzolo, Giovanni, Suzuki, Hisanori, Vinante, Fabrizio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463553/
https://ncbi.nlm.nih.gov/pubmed/23056396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046674
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