Učitavanje...
Proteolytic Processing Regulates Toll-like Receptor 3 Stability and Endosomal Localization
Toll-like receptors (TLRs) 3, 7, and 9 are innate immune receptors that recognize nucleic acids from pathogens in endosomes and initiate signaling transductions that lead to cytokine production. Activation of TLR9 for signaling requires proteolytic processing within the ectodomain by endosome-associ...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463343/ https://ncbi.nlm.nih.gov/pubmed/22865861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.387803 |
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