Crystal Structure and Functional Characterization of the Complement Regulator Mannose-binding Lectin (MBL)/Ficolin-associated Protein-1 (MAP-1)

The human lectin complement pathway activation molecules comprise mannose-binding lectin (MBL) and ficolin-1, -2, and -3 in complex with associated serine proteases MASP-1, -2, and -3 and the non-enzymatic small MBL associated protein or sMAP. Recently, a novel plasma protein named MBL/ficolin-assoc...

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Détails bibliographiques
Auteurs principaux: Skjoedt, Mikkel-Ole, Roversi, Pietro, Hummelshøj, Tina, Palarasah, Yaseelan, Rosbjerg, Anne, Johnson, Steven, Lea, Susan M., Garred, Peter
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463328/
https://ncbi.nlm.nih.gov/pubmed/22854970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.386680
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