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Human Telomerase Reverse Transcriptase (hTERT) Is a Novel Target of the Wnt/β-Catenin Pathway in Human Cancer

Telomerase activation plays a critical role in human carcinogenesis through the maintenance of telomeres, but the activation mechanism during carcinogenesis remains unclear. The human telomerase reverse transcriptase (hTERT) promoter has been shown to promote hTERT gene expression selectively in tum...

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Bibliographic Details
Main Authors: Zhang, Yong, Toh, LingLing, Lau, Peishan, Wang, Xueying
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463325/
https://ncbi.nlm.nih.gov/pubmed/22854964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368282
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