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Betaine Homocysteine Methyltransferase Is Active in the Mouse Blastocyst and Promotes Inner Cell Mass Development

Methyltransferases are an important group of enzymes with diverse roles that include epigenetic gene regulation. The universal donor of methyl groups for methyltransferases is S-adenosylmethionine (AdoMet), which in most cells is synthesized using methyl groups carried by a derivative of folic acid....

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Detalhes bibliográficos
Main Authors: Lee, Martin B., Kooistra, Megan, Zhang, Baohua, Slow, Sandy, Fortier, Amanda L., Garrow, Timothy A., Lever, Michael, Trasler, Jacquetta M., Baltz, Jay M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463305/
https://ncbi.nlm.nih.gov/pubmed/22847001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365478
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