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Crystal structure of IFIT2 (ISG54) predicts functional properties of IFITs

Interferon carries out its cellular effects, including its antiviral effects, by inducing the synthesis of many new proteins, amongst which is the IFIT (ISG56) family of proteins. The first crystal structure of an IFIT, reported by Yang et al., revealed several functional properties of the protein t...

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Autori principali: Sen, Ganes C, Fensterl, Volker
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463260/
https://ncbi.nlm.nih.gov/pubmed/22964712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.130
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