Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV Neuropathogenesis

Interferon protects mice from vesicular stomatitis virus (VSV) infection and pathogenesis; however, it is not known which of the numerous interferon-stimulated genes (ISG) mediate the antiviral effect. A prominent family of ISGs is the interferon-induced with tetratricopeptide repeats (Ifit) genes c...

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Main Authors: Fensterl, Volker, Wetzel, Jaime L., Ramachandran, Srividya, Ogino, Tomoaki, Stohlman, Stephen A., Bergmann, Cornelia C., Diamond, Michael S., Virgin, Herbert W., Sen, Ganes C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355090/
https://ncbi.nlm.nih.gov/pubmed/22615570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002712
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