RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB

Many cell surface signaling receptors, such as the neurotrophin receptor, TrkB, have emerged as potential therapeutic targets for diverse diseases. Reduced activation of TrkB in particular is thought to contribute to neurodegenerative diseases. Unfortunately, development of therapeutic reagents that...

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Autors principals: Huang, Yang Zhong, Hernandez, Frank J., Gu, Bin, Stockdale, Katie R., Nanapaneni, Kishore, Scheetz, Todd E., Behlke, Mark A., Peek, Andrew S., Bair, Thomas, Giangrande, Paloma H., McNamara, James O.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463223/
https://ncbi.nlm.nih.gov/pubmed/22752556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078220
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