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RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB

Many cell surface signaling receptors, such as the neurotrophin receptor, TrkB, have emerged as potential therapeutic targets for diverse diseases. Reduced activation of TrkB in particular is thought to contribute to neurodegenerative diseases. Unfortunately, development of therapeutic reagents that...

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Détails bibliographiques
Auteurs principaux: Huang, Yang Zhong, Hernandez, Frank J., Gu, Bin, Stockdale, Katie R., Nanapaneni, Kishore, Scheetz, Todd E., Behlke, Mark A., Peek, Andrew S., Bair, Thomas, Giangrande, Paloma H., McNamara, James O.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463223/
https://ncbi.nlm.nih.gov/pubmed/22752556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078220
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