Stimulation of de novo synthesis of cytochrome P-450 by phenobarbital in primary nonproliferating cultures of adult rat hepatocytes.
Primary monolayer cultures of nonproliferating parenchymal cells prepared from adult rat liver and maintained in serum-free medium responded to additions of phenobarbital with concentration-dependent increases in synthesis and accumulation of a cytochrome P-450 protein immunochemically and catalytic...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1982
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6953437/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.9.2922 |
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