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Stimulation of de novo synthesis of cytochrome P-450 by phenobarbital in primary nonproliferating cultures of adult rat hepatocytes.

Primary monolayer cultures of nonproliferating parenchymal cells prepared from adult rat liver and maintained in serum-free medium responded to additions of phenobarbital with concentration-dependent increases in synthesis and accumulation of a cytochrome P-450 protein immunochemically and catalytic...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Newman, S, Guzelian, P S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1982
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346320/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6953437/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.9.2922
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