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Phorbol ester induction of leukemic cell differentiation is a membrane-mediated process.

Phorbol esters are potent inducers of macrophage-like differentiation in the HL-60 promyelocytic leukemia cell line. The sequence of events by which they bring about this transition is poorly understood. However, it is known that phorbol esters bind to the surface membrane of HL-60 cells and to vari...

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Detalles Bibliográficos
Main Authors: Cooper, R A, Braunwald, A D, Kuo, A L
Formato: Artigo
Idioma:Inglês
Publicado: 1982
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC346307/
https://ncbi.nlm.nih.gov/pubmed/6953435
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