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Phorbol ester induction of leukemic cell differentiation is a membrane-mediated process.

Phorbol esters are potent inducers of macrophage-like differentiation in the HL-60 promyelocytic leukemia cell line. The sequence of events by which they bring about this transition is poorly understood. However, it is known that phorbol esters bind to the surface membrane of HL-60 cells and to vari...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Cooper, R A, Braunwald, A D, Kuo, A L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346307/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6953435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.9.2865
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