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CXCL1-Deficient Mice Are Highly Sensitive to Pseudomonas aeruginosa but Not Herpes Simplex Virus Type 1 Corneal Infection

PURPOSE. To determine the role of the chemokine CXCL1 on leukocyte recruitment, cytokine production and host resistance during HSV-1 and Pseudomonas aeruginosa infection. METHODS. Viral titer and bacterial load were compared following infection of wild-type (WT) and CXCL1(−/−) mice. Corneal leukocyt...

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Bibliografiske detaljer
Main Authors: Bryant-Hudson, Katie M., Carr, Daniel J. J.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462609/
https://ncbi.nlm.nih.gov/pubmed/22952118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10400
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