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Herpes Simplex Virus Type 2-Induced Mortality following Genital Infection Is Blocked by Anti-Tumor Necrosis Factor Alpha Antibody in CXCL10-Deficient Mice

The role of tumor necrosis factor alpha (TNF-α) was evaluated for CXCL10-deficient (CXCL10(−/−)) mice which succumbed to genital herpes simplex virus type 2 (HSV-2) infection and possessed elevated levels of virus and TNF-α but not other cytokines in the central nervous system (CNS) and vaginal tiss...

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Bibliografiske detaljer
Main Authors: Thapa, Manoj, Carr, Daniel J. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566256/
https://ncbi.nlm.nih.gov/pubmed/18684827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00931-08
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