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Catalytic promiscuity of a bacterial α-N-methyltransferase

The posttranslational methylation of N-terminal α-amino groups (α-N-methylation) is a ubiquitous reaction found in all domains of life. Although this modification usually occurs on protein substrates, recent studies have shown that it also takes place on ribosomally synthesized natural products. Her...

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Détails bibliographiques
Auteurs principaux: Zhang, Qi, van der Donk, Wilfred A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462432/
https://ncbi.nlm.nih.gov/pubmed/22841713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.07.050
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