Development of inflammation-induced hyperalgesia and allodynia is associated with the upregulation of extrasynaptic AMPA receptors in tonically firing lamina II dorsal horn neurons

Persistent peripheral inflammation changes AMPA receptor (AMPAR) trafficking in dorsal horn neurons by promoting internalization of GluR2-containing, Ca(2+)-impermeable AMPARs from the synapses and by increasing insertion of GluR1-containing, Ca(2+)-permeable AMPARs in extrasynaptic plasma membrane....

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kopach, Olga, Viatchenko-Karpinski, Viacheslav, Belan, Pavel, Voitenko, Nana
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2012
Ämnen:
Physiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462428/
https://ncbi.nlm.nih.gov/pubmed/23060815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00391
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