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PKCα is required for inflammation-induced trafficking of extrasynaptic AMPA receptors in tonically firing lamina II dorsal horn neurons during the maintenance of persistent inflammatory pain
Persistent inflammation promotes internalization of synaptic GluR2-containing Ca(2+)-impermeable AMPA receptors (AMPARs) and insertion of GluR1-containing Ca(2+)-permeable AMPARs at extrasynaptic sites in dorsal horn neurons. Previously we have shown that internalization of synaptic GluR2-containing...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564511/ https://ncbi.nlm.nih.gov/pubmed/23374940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2012.10.015 |
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