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Revisiting the Role of the Immunoproteasome in the Activation of the Canonical NF-κB Pathway

The discovery of NF-κB signaling pathways has greatly enhanced our understanding of inflammatory and immune responses. In the canonical NF-κB pathway, the proteasomal degradation of IκBα, an inhibitory protein of NF-κB, is widely accepted to be a key regulatory step. However, contradictory findings...

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Detalhes bibliográficos
Main Authors: Jang, Eun Ryoung, Lee, Na-Ra, Han, Songhee, Wu, Ying, Sharma, Lalit Kumar, Carmony, Kimberly Cornish, Marks, James, Lee, Do-Min, Ban, Jung-Ok, Wehenkel, Marie, Hong, Jin Tae, Kim, Kyung Bo, Lee, Wooin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462293/
https://ncbi.nlm.nih.gov/pubmed/22722901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mb25125f
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