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Increasing MuSK Activity Delays Denervation and Improves Motor Function in ALS Mice
ALS is a devastating disease, progressing from detachment of motor nerve terminals to complete muscle paralysis and lethal respiratory failure within five years of diagnosis. Genetic studies have linked mutations in several genes to ALS, and mice bearing mutations in SOD1 recapitulate hallmark featu...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462266/ https://ncbi.nlm.nih.gov/pubmed/22939980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.004 |
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