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Lipoxin A(4) inhibits platelet-activating factor inflammatory response and stimulates corneal wound healing of injuries that compromise the stroma

Platelet-activating factor (PAF) is a bioactive lipid mediator with strong inflammatory properties. PAF induces the expression and activation of metalloproteinase-9 (MMP-9) in corneal epithelial cells and myofibroblasts, and delays epithelial wound healing in an organ culture system. Lipoxin A(4) (L...

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Detalhes bibliográficos
Main Authors: Kakazu, Azucena, He, Jiucheng, Kenchegowda, Sachidananda, Bazan, Haydee E.P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462263/
https://ncbi.nlm.nih.gov/pubmed/22828048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.07.008
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