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Novel RvD6 stereoisomer induces corneal nerve regeneration and wound healing post-injury by modulating trigeminal transcriptomic signature

The high-density corneal innervation plays a pivotal role in sustaining the integrity of the ocular surface. We have previously demonstrated that pigment epithelium-derived factor (PEDF) plus docosahexaenoic acid (DHA) promotes corneal nerve regeneration; here, we report the mechanism involved and t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pham, Thang L., Kakazu, Azucena H., He, Jiucheng, Jun, Bokkyoo, Bazan, Nicolas G., Bazan, Haydee E. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067818/
https://ncbi.nlm.nih.gov/pubmed/32165657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61390-8
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