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3D Domain Swapping Causes Extensive Multimerisation of Human Interleukin-10 When Expressed In Planta

Heterologous expression platforms of biopharmaceutical proteins have been significantly improved over the last decade. Further improvement can be established by examining the intrinsic properties of proteins. Interleukin-10 (IL-10) is an anti-inflammatory cytokine with a short half-life that plays a...

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Autori principali: Westerhof, Lotte B., Wilbers, Ruud H. P., Roosien, Jan, van de Velde, Jan, Goverse, Aska, Bakker, Jaap, Schots, Arjen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462211/
https://ncbi.nlm.nih.gov/pubmed/23049703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046460
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