3D Domain Swapping Causes Extensive Multimerisation of Human Interleukin-10 When Expressed In Planta

Heterologous expression platforms of biopharmaceutical proteins have been significantly improved over the last decade. Further improvement can be established by examining the intrinsic properties of proteins. Interleukin-10 (IL-10) is an anti-inflammatory cytokine with a short half-life that plays a...

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Detalhes bibliográficos
Principais autores: Westerhof, Lotte B., Wilbers, Ruud H. P., Roosien, Jan, van de Velde, Jan, Goverse, Aska, Bakker, Jaap, Schots, Arjen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462211/
https://ncbi.nlm.nih.gov/pubmed/23049703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046460
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