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Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation
Streptococcus pyogenes M/emm3 strains have been epidemiologically linked with enhanced infection severity and risk of streptococcal toxic shock syndrome (STSS), a syndrome triggered by superantigenic stimulation of T cells. Comparison of S. pyogenes strains causing STSS demonstrated that emm3 strain...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science
2012
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462185/ https://ncbi.nlm.nih.gov/pubmed/23049698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046376 |
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