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Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac development

Cardiac development requires interplay between the regulation of gene expression and the assembly of functional sarcomeric proteins. We report that UNC-45b recessive loss-of-function mutations in C3H and C57BL/6 inbred mouse strains cause arrest of cardiac morphogenesis at the formation of right hea...

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Detalhes bibliográficos
Main Authors: Chen, Daisi, Li, Shumin, Singh, Ram, Spinette, Sarah, Sedlmeier, Reinhard, Epstein, Henry F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462083/
https://ncbi.nlm.nih.gov/pubmed/22553207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.106435
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