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The cytochrome P-450-depleted animal: an experimental model for in vivo studies in chemical biology.
An experimental method is described to deplete markedly in vivo the cytochrome P-450 content of liver for prolonged periods of time. The method uses the synthetic metalloporphyrin cobalt-heme (cobalt protoporphyrin IX), which possesses the dual biological properties of repressing delta-aminolevulina...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.7.2384 |
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