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Interferon-gamma enhances radiation-induced cell death via downregulation of Chk1

Interferon-gamma (IFNγ) is a cytokine with roles in immune responses as well as in tumor control. Interferon is often used in cancer treatment together with other therapies. Here we report a novel approach to enhancement of cancer cell killing by combined treatment of IFNγ with ionizing radiation. W...

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Detalhes bibliográficos
Main Authors: Kim, Kwang Seok, Choi, Kyu Jin, Bae, Sangwoo
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461808/
https://ncbi.nlm.nih.gov/pubmed/22825336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20990
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