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Mutant of Chinese hamster ovary cells with altered mannose 6-phosphate receptor activity is unable to synthesize mannosylphosphoryldolichol.

B4-2-1 is a Chinese hamster ovary cell mutant previously isolated and characterized as deficient in mannose 6-phosphate receptor activity. We show here that B4-2-1 is a pleiotropic mutant, defective in biosynthesis of asparagine-linked oligosaccharides, B4-2-1 is unable to synthesize mannosylphospho...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Stoll, J, Robbins, A R, Krag, S S
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346179/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954541/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.7.2296
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