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The t(4;14) translocation and FGFR3 overexpression in multiple myeloma: prognostic implications and current clinical strategies

Multiple myeloma (MM) is a heterogeneous plasma cell disorder characterized by genetic abnormalities, including chromosomal translocations, deletions, duplications and genetic mutations. Translocations involving the immunoglobulin heavy chain region at chromosome 14q32 are observed in approximately...

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Detalhes bibliográficos
Main Authors: Kalff, A, Spencer, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461707/
https://ncbi.nlm.nih.gov/pubmed/22961061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2012.37
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