Prevention of Diabetic Nephropathy by Sulforaphane: Possible Role of Nrf2 Upregulation and Activation

The present study was to investigate whether sulforaphane (SFN) can prevent diabetic nephropathy in type 1 diabetic mouse model induced by multiple low-dose streptozotocin. Diabetic and age-matched control mice were given SFN at 0.5 mg/kg body weight daily for 3 months. At the end of 3-month SFN tre...

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Detalhes bibliográficos
Main Authors: Cui, Wenpeng, Bai, Yang, Miao, Xiao, Luo, Ping, Chen, Qiang, Tan, Yi, Rane, Madhavi J., Miao, Lining, Cai, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461640/
https://ncbi.nlm.nih.gov/pubmed/23050040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/821936
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