Sanger sequencing in routine KRAS testing: a review of 1720 cases from a pathologist's perspective

BACKGROUND: Sanger sequencing (SS) of PCR products is still the most frequent method to test colorectal cancer for KRAS mutations in routine practice. METHODS: An audit of SS on 1720 routine cases was carried out, taking into account age, gender, specimen type (resection vs biopsies), tumour site (p...

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Detalhes bibliográficos
Main Authors: Malapelle, Umberto, Bellevicine, Claudio, Salatiello, Maria, de Luca, Caterina, Rispo, Elisabetta, Riccio, Palmira, Sparano, Lucianna, De Stefano, Alfonso, Carlomagno, Chiara, Maiello, Francesco Maria, Vita, Giulia, Nappi, Oscar, Troncone, Giancarlo
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461636/
https://ncbi.nlm.nih.gov/pubmed/22872705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2012-200773
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