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In Vitro Selection of Fab Fragments by mRNA Display and Gene-Linking Emulsion PCR

In vitro selection by display methods has been an effective tool for engineering recombinant antibodies. mRNA display based on a cell-free translation system has the advantages of larger library sizes and quicker selection procedures compared with cell-based display methods such as phage display. Ho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sumida, Takeshi, Yanagawa, Hiroshi, Doi, Nobuhide
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461632/
https://ncbi.nlm.nih.gov/pubmed/23050123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/371379
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